Hwa-In (Fine) Han

  • Graduate Student Researcher

I am interested in understanding mechanisms that enhance kidney repair after acute kidney injury. The early phase of my thesis focused much on understanding how our small molecule, PTBA, enhances AKI using larval zebrafish as a model for AKI.  I am also interested in teasing out the complex roles of the innate immune system in aiding and prolonging acute kidney injury in the fish. Right now, I am currently exploring the role of cell cycle delay and arrest in the context of kidney injury.

Education & Training

  • College of William and Mary B.S. in Biology with honors in reproductive physiology

Representative Publications

Brilli Skvarca L, Han HI, Espiritu EB, Missinato MA, Rochon ER, McDaniels MD, Bais AS, Roman BL, Waxman JS, Watkins SC, Davidson AJ, Tsang M, Hukriede NA. Enhancing regeneration after acute kidney injury by promoting cellular dedifferentiation in zebrafish. Dis Model Mech. 2019 Apr 5;12(4). pii: dmm037390. doi: 10.1242/dmm.037390. PubMed PMID: 30890583; PubMed Central PMCID: PMC6505474.

Han HI, Skvarca LB, Espiritu EB, Davidson AJ, Hukriede NA. The role of macrophages during acute kidney injury: destruction and repair. Pediatr Nephrol. 2019 Apr;34(4):561-569. doi: 10.1007/s00467-017-3883-1. Epub 2018 Jan 30. Review. PubMed PMID: 29383444; PubMed Central PMCID: PMC6066473.

Naylor RW, Han HI, Hukriede NA, Davidson AJ. Wnt8a expands the pool of embryonic kidney progenitors in zebrafish. Dev Biol. 2017 May 15;425(2):130-141. doi: 10.1016/j.ydbio.2017.03.027. Epub 2017 Mar 28. PubMed PMID: 28359809.