- About Us
The laboratories in the Dept. of Developmental Biology have a strong focus on organ regeneration. Faculty are interested in understanding the molecular mechanism that drives the regenerative...
We are undertaking a large-scale forward genetic screen in mice using chemical mutagenesis with ethyl nitrosourea (ENU) to recover mutations causing congenital heart defects. This screen was...
Genetic Basis of Human Congenital Heart Disease
Congenital heart disease is one of the most common birth defects, affecting up to 1% of live births. Despite its prevalence, the causes of congenital heart disease are not well understood. A...
Chemical Library Screen
One common research goal of members in the Department of Developmental Biology is to identify small molecules that can be utilized to probe the role of signaling pathways in development. The...
Atlas of Mouse Cardiovascular Development
We constructed a developmental atlas of the mouse cardiovascular system using episcopic fluorescence image capture (EFIC), a histological imaging techniques that provides serial 2D histological...